The 2025 Purdue Boilermakers football team was an American football team that represented Purdue University as a member of the Big Ten Conference during the 2025 NCAA Division I FBS football season. Led by first-year head coach Barry Odom, the Boilermakers played their home games at Ross–Ade Stadium in West Lafayette, Indiana. For the second straight year, the Boilermakers failed to win a single conference game.
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