Columbia is a city in Boone County, Missouri, United States, and its county seat. It was founded in 1821 and had a population of 126,254 as recorded in the 2020 United States census, making it the fourth-most populous city in Missouri. Columbia is a Midwestern college town, home to the University of Missouri, a major research institution also known as MU or Mizzou. In addition to the university and surrounding Downtown Columbia are Stephens College and Columbia College, giving the city its educational focus and nearly 40,000 college students. It is the principal city of the Columbia metropolitan area, population 215,811, and the central city of the nine-county Columbia–Jefferson City–Moberly combined statistical area with 415,747 residents. The city is the fastest-growing municipality in Missouri, with a growth of almost 40% since 2000, and a population estimated at 130,900 in 2024. Columbia is among the most-educated cities in the United States with about half of citizens being college graduates and about a quarter holding advance degrees.