The Clemson–South Carolina rivalry is an American collegiate athletic rivalry between the Clemson University Tigers and the University of South Carolina Gamecocks, the two largest universities in the state of South Carolina. Since 2015, the two compete in the Palmetto Series, which consists of more than a dozen athletic, head-to-head matchups each school year. South Carolina leads the all-sport series 6–1, winning the 2024–2025 series, 7–4. Both institutions are public universities supported by the state, and their campuses are separated by only 132 miles. South Carolina and Clemson have been bitter rivals since 1896, and a heated rivalry continues to this day for a variety of reasons, including the historic tensions regarding their respective charters and the passions surrounding their athletic programs. It has often been listed as one of the best rivalries in college sports.