The Southern Indiana Screaming Eagles are the athletic teams that represent the University of Southern Indiana, located outside Evansville in Vanderburgh County, Indiana, in NCAA Division I intercollegiate sports. The Screaming Eagles compete as members of the Ohio Valley Conference. Southern Indiana had previously been a member of the NCAA Division II Great Lakes Valley Conference from 1978 to 2022, when the school announced it would reclassify to NCAA Division I.