José Luis Gómez may refer to:
- José Luis Centella Gómez, Spanish politician
- José Luis Cruz Flores Gómez, Mexican politician
- José Luis Gómez (actor), Spanish actor and director
- José Luis Gómez (footballer), Argentine footballer
- José Luis Gómez Martínez, Spanish professor
- José Luis Salgado Gómez, Mexican former footballer and manager
- José Luis Viejo Gómez (1949–2014), Spanish road cyclist
- Joselu, born José Luis Gómez Hurtado, Spanish footballer
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