Holmes & Watson is a 2018 mystery comedy film written and directed by Etan Cohen. The film stars Will Ferrell and John C. Reilly as the eponymous characters Sherlock Holmes and Dr. Watson, respectively; with Rebecca Hall, Rob Brydon, Kelly Macdonald, Steve Coogan and Ralph Fiennes in supporting roles. The plot follows the famed detective duo as they set out to find the culprit behind a threat at Buckingham Palace.