Excision may refer to:

• In surgery, the partial removal of an organ, tissue, bone or tumor from a body
• Type II female genital mutilation
• A term used by the Australian government as part of its definition of the Australian migration zone
• Excision theorem in algebraic topology, a branch of mathematics
• Excise, taxes charged on the purchase of goods or services
• Excision (musician), a Canadian dubstep producer from British Columbia.
• Excision (film), a 2012 American horror film