Carlos Varela may refer to:
- Carlos Varela (singer), Cuban singer-songwriter
- Carlos Varela (bandleader), Cuban bandleader of the 1940s-era Orquestra Havana-Madrid
- Carlos Muñiz Varela (1953–1979), Cuban resident of Puerto Rico who was murdered under suspicious circumstances in 1979
- Carlos Varela, Spanish footballer
- Carlos Varela (1918–1964)
- Carlos Varela (wrestler), wrestler from Cuba
- Carlos Mendes Varela, Portuguese-born French rugby league player
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