112 may refer to:

• 112 (number), the natural number following 111 and preceding 113
• 112, the standard emergency phone number in the European Union and on GSM cellphones
• 112 (band), an R&B quartet from Atlanta, Georgia, United States
  • 112 (album), album from the band of the same name
• 112 BC, a year
• AD 112, a year of the Julian calendar
• Copernicium, an element with atomic number 112
• Route 112 (MBTA), a bus route in Massachusetts, United States
• 112
• KFM 112M aircraft engine
• Thai Criminal Code section 112, see Lèse majesté in Thailand
• 112 Iphigenia, a main-belt asteroid